SC/IM/IV Adult weighing 70 kg 10 mg, may be repeated every 3-6 hr as necessary.Non-tolerant patient Max: 20 mg. Max total daily dose: 160 mg. Induction of anesth 0.3-3 mg/kg IV over 10-15 min. Maintenance: 0.25-0.5 mg/kg single IV.
Emotionally unstable patients or history of narcotic abuse. Physical dependence. Avoid abrupt discontinuation & prolonged use. Head injury & increased intracranial pressure; bradycardia. Impaired resp, renal or hepatic function. Patients w/ MI & to undergo surgery of the biliary tract. May impair mental or physical abilities required to perform potentially dangerous tasks eg, driving or operating machinery. Women delivering premature infants. Pregnancy. Childn & neonate.
May exhibit additive effect w/ narcotic analgesic, general anesth, phenothiazines or other tranquilizers, sedatives, hypnotics or other CNS depressants including alcohol.
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