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The dose is dependent on the individual requirement and should be adjusted according to the response of the patient. Although the dose should be individualized, the usual initial oral adult dose is 50 mg twice a day or 100 mg once a day.
Dosage may be increased at one-week interval to as high as 400 mg a day according to the patient's response until optimum hypotensive effect is attained.
The usual oral maintenance dose is 100 mg to 400 mg daily. In some patients, once daily administration of 200 mg METOPROLOL tartrate (NEOBLOC) tablet is usually effective for maintenance dose.
METOPROLOL tartrate (NEOBLOC) tablet may be combined with other antihypertensive agents and/or diuretic combinations for therapeutic advantage.
