Individualized dosage. Adult Initially 50 mg bid or 100 mg once daily. Dosage may be increased at 1-wk interval to as high as 400 mg a day. Maintenance: 100-400 mg daily.
Avoid abrupt w/drawal. May prolong hypoglycemic effect of insulin in diabetic patients especially those w/ labile diabetes. Anesth. Pregnancy (1st trimester).