Chewable tab: The prolonged use of antacids in patients with renal failure should be avoided.
Care should be observed if used by diabetics because of the sugar content in the tablet.
Oral susp: Aluminum hydroxide may cause constipation due to its astringent action, this effect may be balanced by the cathartic effect of the magnesium salts.
Aluminum hydroxide may lead to a phosphate depletion syndrome, particularly in patients on a low phosphate diet eg, malnutrition.
Magnesium salts may cause central nervous depression in the presence of renal insufficiency and should be used with caution in patients with advance renal disease.
In patients with renal impairment, plasma levels of both aluminum and magnesium increase. In these patients, a long-term exposure to high doses of aluminum and magnesium salts may lead to encephalopathy or worsen dialysis osteomalacia.
The prolonged use of antacids in patients with renal failure should be avoided.
Effects on the Ability to Drive or Operate Machinery: None.
Use in pregnancy: Maalox should not be used during pregnancy unless considered essential by the physician.