Partial onset seizures Adult ≥16 yr Initially 1,000 mg/day (500 mg bid).
Childn 4 to <16 yr Initially 20 mg/kg in 2 divided doses, may be increased every 2 wk by increments of 20 mg/kg. Max: 60 mg/kg (30 mg/kg bid) daily,
6 mth to <4 yr Initially 20 mg/kg in 2 divided doses, may be increased in 2 wk by increments of 20 mg/kg. Max: 50 mg/kg (25 mg/kg bid) daily,
1 to <6 mth Initially 14 mg/kg in 2 divided doses (7 mg/kg bid).
Myoclonic seizures Patient ≥12 yr 1,000 mg/day (500 mg bid), may be increased by 1,000 mg/day every 2 wk. Max: 3,000 mg daily.
Primary generalized tonic-clonic seizures Adult ≥16 yr 1,000 mg/day (500 mg bid).
Childn 6 to <16 yr 20 mg/kg in 2 divided doses (10 mg/kg bid).
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