Lacipil Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Lacidipine

Indications/Uses

HTN either alone or in combination w/ other antihypertensive agents.

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Dosage/Direction for Use

Initially 2 mg once daily taken at the same time each day; may be increased to 4 mg & if necessary to 6 mg.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Severe aortic stenosis.

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Special Precautions

Preexisting abnormalities in SA & AV node activity, congenital or documented acquired QT prolongation, poor cardiac reserve, unstable angina pectoris, recent MI. Concomitant use w/ medications that prolong the QT interval eg, class I & III antiarrhythmics, TCAs, some antipsychotics, antibiotics (eg, erythromycin) & some antihistamines (eg, terfenadine). Hepatic impairment. Pregnancy & lactation. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache, dizziness; palpitation, tachycardia; flushing; stomach discomfort, nausea; skin rash (erythema, itching); polyuria; asthenia, edema; reversible increase in alkaline phosphatase.

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Drug Interactions

Additive hypotensive effect w/ antihypertensive agents (eg, diuretics, β-blockers, ACE inhibitors). May increase plasma levels w/ cimetidine. Altered bioavailability w/ grapefruit juice. Reverse decreased renal plasma flow & GFR induced by cyclosporin. Concurrent use w/ CYP3A4 inhibitors & inducers.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Lacipil detailed prescribing information

Storage

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Action

View Lacipil mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Calcium Antagonists

ATC Classification

C08CA09 - lacidipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Lacipil tab 2 mg

Packing/Price

56's

Form

Lacipil tab 4 mg

Packing/Price

56's

Form

Lacipil tab 6 mg

Packing/Price

28's

Lacipil

lacidipine

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig