Ivcort Adverse Reactions

Since Hydrocortisone sodium succinate for injection is normally employed on a short term basis it is unlikely that side effects will occur; however, the possibility of side effects attributable to corticosteroid therapy should be recognised.
Such side effects include: Parental corticosteroid therapy: Anaphylactoid reaction, e.g. Bronchospasm, hypopigmentation or hyper- pigmentation, subcutaneous and cutaneous atrophy, sterile abscess, laryngeal oedema and urticaria.
Gastrointestinal: Dyspepsia, peptic ulcer with perforation and haemorrhage, abdominal distension, oesophageal ulceration, oesophageal candidiasis, acute pancreatitis, perforation of bowel, Increase in alanine transaminase (ALT/SGPT) aspartate transaminase (AST/SGOT) and alkaline phosphatase have been observed following corticosteroid treatment.
Anti-inflammatory and Immunosuppressive effects: Increased susceptibility and severity of infections with suppression of clinical symptoms and sign, opportunistic infections, may suppress reactions to skin tests, recurrence of dormant tuberculosis.
Musculoskeletal: Proximal myopathy, osteoporosis, vertebral and long bone fractures, avascular osteonecrosis, tendon rupture, aseptic necrosis, muscle weakness.