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Batroxobin: May cause thromboembolism.
Coagulation factor agents (e.g., Eptacog-alfa): Coagulation may be further activated at sites with enhanced local fibrinolysis such as the oral cavity.
Hemocoagulase: Coadministration at high doses may cause thrombosis.
Others: Simultaneous treatment with anticoagulants should be under the strict supervision of an expert physician.
Tranexamic acid may counteract the thrombolytic effect of fibrinolytic preparations.
Concomitant therapy with tissue plasminogen activators may decrease the efficacy of both tranexamic acid and tissue plasminogen activators. Thus, exercise caution if a woman taking tranexamic acid requires tissue plasminogen activators.
