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Trichomoniasis: Adult: Given orally either as a single 2 g dose, as a 2-day course of 800 mg in the morning and 1.2 g in the evening, as a 7-day course of 600 mg to 1 g daily in two or three divided doses.
Anaerobic bacterial infections: Given orally in an initial dose of 800 mg followed by 400 mg every 8 hours, usually for about 7 days.
Amoebiasis: Adult: Given in oral doses of 400 to 800 mg three times daily for 5 to 10 days. An alternative adult dose is 1.5 to 2.5 g as a single daily dose for 2 to 3 days.
Children: Aged 1 to 3 years may be given one-quarter, those aged 3 to 7 years one-third, and those aged 7 to 10 years one-half the total adult daily dose; alternatively 35 to 50 mg/kg in divided doses.
Giardiasis: Adult: Usual oral dose is 2 g once daily for 3 successive days, or 400 mg three times daily for 5 days, or 500 mg twice daily for 7 to 10 days.
Children: Alternative schedule for children is 15 mg/kg daily in divided doses.
