Increased Heart Rate, Blood Pressure, Ventricular Ectopic Activity, Angina or chest pain and Palpitation: A 10 to 20 mm increase in systolic blood pressure and an increase in heart rate of 5 to 15 beats/minute have been noted in most patients. Approximately 5% of patients have had increased premature ventricular beats during infusion. These effects are dose related. Dosage should be reduced or temporarily stopped.
Miscellaneous Uncommon Effects: The following adverse effects, if they occur: nausea, headache, shortness of breath, hypertension, dyspnea, paraesthesias, vomiting & leg cramp. Long-Term-Safety Infusion of up to 72 hours have revealed no adverse effects other than those seen with shorter infusions.