Dobuzef Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Dobutamine HCl

Indications/Uses

Increase heart contractility in acute heart failure associated w/ cardiogenic shock & MI. Cardiac surgery, +ve & expiratory pressure ventilation.

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Dosage/Direction for Use

IV infusion Acute heart failure 2.5-10 mcg/kg/min. Dose range: 0.5-40 mcg/kg/min. Alternative to exercise in cardiac stress testing 5 mcg/kg/min for 8 min then increased by increments of 5 mcg/kg/min up to a max of 20 or 40 mcg/kg/min.

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Overdosage

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Contraindications

Hypersensitivity. Patients w/ idiopathic hypertrophic subaortic stenosis.

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Special Precautions

Avoid abrupt w/drawal. Discontinue use if arrhythmia or marked ST-segment depression occurs. Continuously monitor ECG, BP, pulmonary wedge pressure & cardiac output. Correct hypovolemia before treatment. Cardiogenic shock complicated by severe hypotension; marked mechanical obstruction eg, severe valvular aortic stenosis; acute MI. Pregnancy. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Increased heart rate, BP, ventricular ectopic activity, angina or chest pain & palpitation.

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Drug Interactions

Increased cardiac output w/ concomitant use of nitroprusside increased peripheral resistance w/ β-adrenergic blocking agents. May cause ventricular arrhythmias w/ general anesth eg, halothane & cyclopropene.

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Storage

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Description

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Action

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MIMS Class

Cardiac Drugs

ATC Classification

C01CA07 - dobutamine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.

Regulatory Classification

Presentation/Packing

Form

Dobuzef soln for inj 50 mg/mL

Packing/Price

5 mL x 5 × 1's (P2,713.7/box)

Dobuzef

dobutamine

Manufacturer:

Metro Pharma

Distributor:

Metro Drug