Dimezine Dosage/Direction for Use

Adults: 1 tablet three times daily.
Elderly: Dosage as for adults.
Renal impairment: Cinnarizine & Dimenhydrinate combination should be used with caution in patients with mild to moderate renal impairment. Cinnarizine & Dimenhydrinate combination should not be used by patients with a creatinine clearance of < 25mL/min (severe renal impairment).
Hepatic impairment: No studies in patients with hepatic impairment are available. Cinnarizine & Dimenhydrinate combination should not be used by patients with severe hepatic impairment.
Pediatric population: The safety and efficacy of Cinnarizine & Dimenhydrinate combination in children and adolescents under the age of 18 years has not been established. No data are available.
In general, the duration of treatment should not exceed four weeks. The physician shall decide whether longer treatment is required.
Method of administration: Cinnarizine & Dimenhydrinate combination tablets are to be taken unchewed, with some liquid after meals.