Chronic simple glaucoma 250 mg-1 g/24 hr in divided doses.
Secondary glaucoma/pre-op treatment of some cases of acute congestive glaucoma 250 mg 4 hrly. In some acute cases, initially 500 mg then 125-250 mg 4 hrly.
Epilepsy 8-30 mg/kg in divided doses. Max: 375-1,000 mg daily.
CHF 250-375 mg once daily in the morning.
Drug-induced edema 250-375 mg once daily for 1-2 days, alternating w/ a day of rest.