Syrup: The most frequent adverse reactions of Salbutamol in adults and older children are tremors (particularly the hands), nervousness and shakiness. Other reported reactions are headache, dizziness, hyperactivity and excitement, tachycardia, palpitation, peripheral vasodilation, epistaxis, cough, increased appetite, epigastric pain or stomachache, insomnia/sleeplessness, weakness, and rarely muscle cramps.
The following side effects are noted in young children: excitement, nervousness, hyperkinesia, sleeplessness, emotional lability, fatigue, tachycardia, pallor, gastrointestinal symptoms, and conjunctivitis. Erythema multiforme or Stevens-Johnson syndrome has been reported rarely with administration of oral Salbutamol in children.
Potentially serious hypokalemia has also been reported.
Cases of urticaria, angioedema, rash, anaphylaxis, paradoxical bronchospasm, oropharyngeal edema, and arrhythmias (including atrial fibrillation, supraventricular tachycardia, and extrasystoles) have also been noted after the use of oral Salbutamol.
Salbutamol, like other sympathomimetic agents, can also cause central nervous system stimulation, angina, nausea, unusual taste, and drying or irritation of the oropharynx.
Pulmoneb: Tremors (particularly the hands), nervousness, dizziness, headache, sleeplessness/insomnia, tachycardia, palpitations, chest pain, hypertension, peripheral vasodilation, increased coughing, wheezing, asthma exacerbation, bronchitis, nasal congestion, rhinitis, pharyngitis, sinusitis, viral infection, increased hemoptysis in patients with pre-existing hemoptysis, hoarseness, otitis media, nausea, vomiting, diarrhea, hypertonia, asthenia, back pain, fever, lymphadenopathy, and rarely, muscle cramps have been observed after administration of nebulized Salbutamol. Potentially serious hypokalemia has also been reported.
Hypersensitivity reactions (such as urticaria, angioedema, rash, bronchospasm, anaphylaxis, oropharyngeal edema, hypotension, and collapse) and arrhythmias (such as atrial fibrillation, supraventricular tachycardia, and extrasystoles) have also been noted after the use of orally inhaled Salbutamol.
Salbutamol, like other sympathomimetic agents, can also cause angina, vertigo, central nervous system stimulation, paradoxical bronchospasm, and dry mouth.