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In cases of chronic use/abuse, the loss of potassium can potentiate the effect of cardiac glycosides and influence the action of antiarrhythmics. Loss of potassium can be enhanced in combination with certain diuretics (agents promoting the excretion of urine), cortisone or cortisone-like substances (adrenocortical steroids) and liquorice roots.
The absorption of concurrently administered drugs from the gastro-intestinal tract into the blood stream can be delayed. A reduction of insulin dose can be required in insulin-dependent diabetics.
