Adeflo

Adeflo

salmeterol + fluticasone

Manufacturer:

Cathay Drug

Distributor:

Cathay Drug
Concise Prescribing Info
Contents
Per 50 mcg/250 mcg inhalation powd cap Salmeterol xinafoate 50 mcg, fluticasone propionate 250 mcg. Per 50 mcg/500 mcg inhalation powd cap Salmeterol xinafoate 50 mcg, fluticasone propionate 500 mcg
Indications/Uses
Maintenance & treatment of mild, moderate & severe persistent asthma in patients >5 yr & in patients w/ COPD.
Dosage/Direction for Use
Adult & adolescent ≥12 yr 1 inhalation bid (morning & evening), approx 12 hr apart. COPD 1 inhalation bid (morning & evening), approx 12 hr apart.
Contraindications
Hypersensitivity. Previous history of paradoximal bronchospasm.
Special Precautions
Infection of nasal passages & sinuses, recent nasal surgery or injury. Do not use as single agent for asthma control. Discontinue use then shift to short acting selective β2-agonist if breakthrough asthma symptoms or acute asthma exacerbations occur. Childn (including <4 yr). Pregnancy & lactation.
Adverse Reactions
Fine tremor of skeletal muscle (particularly the hands), palpitations, tachycardia, nervous tensions, headaches, peripheral vasodilatation; paradoxical bronchospasm, angioedema, urticaria, hypotension & collapse.
Drug Interactions
Increased risk of hypokalemia w/ other β2-agonist, corticosteroids, diuretics or xanthines. Enhanced metabolism w/ barbiturates, carbamazepine, phenytoin, primidone or rifampicin. Increased plasma conc w/ OCs or ritonavir. Excessive K loss w/ K-depleting diuretics eg thiazides or furosemide.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03AK06 - salmeterol and fluticasone ; Belongs to the class of adrenergics in combination with corticosteroids or other drugs, excluding anticholinergics. Used in the treatment of obstructive airway diseases.
Presentation/Packing
Form
Adeflo 50 mcg/250 mcg inhalation powd cap
Packing/Price
32's (P343.28/box);40's (P466.2/box)
Form
Adeflo 50 mcg/500 mcg inhalation powd cap
Packing/Price
32's (P480.2/box);40's (P652.4/box)
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