Relief of acute gout & for the prophylaxis of acute attacks particularly during the 1st few mth of treatment w/ allopurinol or uricosurics. Other conditions including amyloidosis, Behcet's syndrome, familial Mediterranean fever, ITP, pericarditis, primary biliary cirrhosis & pyoderma gangrenosum.
May cause colchicine toxicity w/ clarithromycin, erythromycin, or tolbutamide. Increased serum uric acid & interfere activity w/ thiazide diuretics. May cause muscle disorders w/ ciclosporin. May impair absorption of vit B12.
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