GERD 20 mg once daily for 4 wk. Dyspepsia 10-20 mg daily for 2-4 wk. PUD 20 mg daily as single dose or 40 mg in severe cases. NSAID-associated ulceration 20 mg daily. Zollinger-Ellison syndrome 60 mg once daily. Acid aspiration prophylaxis during general anesth 40 mg in the evening before surgery & further 40 mg 2-6 hr before the procedure.
May increase GI pH & reduced absorption of ampicillin esters, Fe salts or ketoconazole. Decrease in hepatic metabolism, delayed elimination & increase blood conc of anticoagulants (coumarin or indandione-derivative), diazepam or phenytoin. Increase leukopenic &/or thrombocytopenic effects w/ bone marrow depressants.
A02BC01 - omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
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