Sita-Met Description

SITA-Met Tablet 50/500 mg: Each film coated tablet contains: Sitagliptin phosphate monohydrate equivalent to Sitagliptin 50 mg, Metformin HCl B.P. 500 mg.
SITA-Met Tablet 50/1000 mg: Each film coated tablet contains: Sitagliptin phosphate monohydrate equivalent to Sitagliptin 50 mg, Metformin HCl B.P. 1000 mg.
Sita-Met (sitagliptin/metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: sitagliptin and metformin hydrochloride.
Sitagliptin: Sitagliptin is an orally-active inhibitor of dipeptidyl peptidase-4 (DPP-4) enzyme. Sitagliptin is present in Sita-Met tablets in the form of sitagliptin phosphate monohydrate. Slows the inactivation of incretin hormones.
Metformin hydrochloride: Metformin hydrochloride decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Metformin hydrochloride (N, N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents.