Policresulen: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Vaginal
Cervicitis, Vaginitis

Adult: As supp: Insert 1 supp deep into vagina every other day at bedtime. Treatment duration depends on severity of condition.

Special Precautions

Pregnancy and lactation.

Adverse Reactions

Significant: Local irritation.
Reproductive system and breast disorders: Vaginal dryness, vaginal discharge.

Patient Counseling Information

Avoid sexual intercourse during and 7 days after treatment. Avoid use of irritant soap during treatment. Not recommended for use during menstruation.

Action

Description: Policresulen is an organic acid with a topical healing effect. It promotes haemostasis by enabling blood protein coagulation and allowing contraction of muscle fibres of small calibre blood vessels, and chemical debridement through interaction with devitalised plasma membrane phospholipid molecules, thus causing denaturation of cellular proteins allowing for their removal. Its acidity and coagulating properties provide antimicrobial effects against staphylococcus spp, streptococcus spp, and Candida albicans.
Synonym: Metacresolsuphonic acid-formaldehyde
Pharmacokinetics:
Excretion: Elimination half-life: 4-5 hours.

Chemical Structure

Storage

Store below 25°C. Protect from light.

MIMS Class

Preparations for Vaginal Conditions

ATC Classification

G01AX03 - policresulen ; Belongs to the class of other antiinfectives and antiseptics. Used in the treatment of gynecological infections.
D08AE02 - policresulen ; Belongs to the class of phenol and derivatives antiseptics. Used in the treatment of dermatological diseases.

References

Anon. Policresulen. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 13/04/2021.

Buckingham R (ed). Policresulen. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 13/04/2021.

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