As there are no adequate and well-controlled studies in pregnant women and lactating mothers with glimepiride, Perglim should not be used during pregnancy unless clearly needed. Recent studies indicate that abnormal blood glucose levels during pregnancy may lead to congenital abnormalities.
Similarly, caution should be exercised while administering Perglim to lactating mothers. A decision whether to discontinue nursing or the drug should be taken depending on the importance of the drug to the mother.