Oestrogel Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

17-β estradiol

Indications/Uses

HRT for problems due to oestrogen deficiency linked to menopause. Prevention of post-menopausal osteoporosis for women w/ increased risk of fracture & showing intolerance or contraindication to other treatments employed in the prevention of osteoporosis.

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Dosage/Direction for Use

Apply 2.5 g (1 graduated measure) over large surface of skin (on the arms, upper part of the bottom & thighs, lower part of the abdomen, lumbar region) daily for 24-28 days per mth.

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Overdosage

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Contraindications

Hypersensitivity. History or current venous or arterial thromboembolic diseases (phlebitis, pulmonary embolism, angina pectoris, MI, cerebral vascular incidents); breast, uterine or any other oestrogen-dependent cancer; endometrial hyperplasia; undiagnosed vag bleeding; certain liver illnesses; porphyria.

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Special Precautions

Not to be applied to the breasts or mucous membranes. Increased risk of thromboembolic disease, breast or uterine cancer & CV incident or cerebral vascular problem. HTN, diabetes, endometriosis, uterine fibroma, hepatic or biliary problems, epilepsy, migraines or severe headaches, renal or cardiac otospongiosis. Prolonged bed rest or planned surgery. Bleeding. Perform medical exam prior to & periodically in the course of treatment. Carry out regular clinical exam of the breasts especially in cases of family history of breast cancer or if patient has cysts or lumps in the breasts. Not to be taken during pregnancy or lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Breast tension; genital bleedings; abdominal pain & swelling; nausea; headaches; painful periods; vag discharge.

Drug Interactions

Carbamazepine, oxcarbazepine, phenobarb, phenytoin, rifabutin, rifampicin, ritonavir, nelfinavir, nevirapine, efavirenz or St. John's wort prep.

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Storage

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Description

View Oestrogel description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Oestrogens, Progesterones & Related Synthetic Drugs

ATC Classification

G03CA03 - estradiol ; Belongs to the class of natural and semisynthetic estrogens used in estrogenic hormone preparations.

Regulatory Classification

POM

Presentation/Packing

Form

Oestrogel gel 0.06%

Packing/Price

80 g x 1's

Oestrogel

estradiol

Manufacturer:

Besins

Distributor:

AA Medical