The dosage and route vary according to the susceptibility of the causative organisms, the severity of the infection and the overall condition and renal function of the patient. (See Table 3.)

Children 2 months to 16 years: The maximum dose should not exceed that for the adults. Usual Recommended Dose: 50 mg/kg/dose every 12 hrs (every 8 hrs for febrile neutropenic patients).
Administration: For direct IV administration, constitute the 500 mg, 1 g or 2 g vial, and add an appropriate quantity of the resulting solution to an IV container with one of the compatible IV fluids. The resulting solution should be administered over approximately 30 min.
For IM administration, Novapime should be constituted with one of the following diluents: Sterile water for injection, 0.9% sodium chloride, 5% dextrose injection, 0.5% or 1% lidocaine hydrochloride or sterile bacteriostatic water for injection. (See Table 4.)
