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Symptoms: Hypocalcaemia, hypophosphataemia and upper gastrointestinal adverse events eg, upset stomach, heartburn, oesophagitis, gastritis or ulcer, may result from oral overdosage.
Treatment: No specific information is available on the treatment of overdosage with alendronate. Milk or antacids should be given to bind alendronate. Owing to the risk of oesophageal irritation, vomiting should be induced and the patient should remain fully upright.
