Loperamide - oral


Patient Medicine Information
Why do I need this medicine?
Loperamide helps to treat diarrhoea.

It slows down the movement of the gut contents and makes the stools firmer and less watery. It also helps to reduce the number of times you need to run to the toilet.

Loperamide may also be used to treat diarrhoea associated with inflammatory bowel disease (inflammation of the digestive tract).

This medicine may also be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Loperamide exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food.

Loperamide is available as a capsule, oral solution or suspension, conventional tablet, and an orally disintegrating (orodispersible) tablet.

If you are taking the capsule or conventional tablet, swallow it whole with a glass of water.

If you are taking an oral solution or suspension, shake the bottle well before you take it to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure out your dose.

If you are taking the orally disintegrating (orodispersible) tablet:
  1. Remove it from the foil only just before you take it. Do not leave the orodispersible tablet exposed to air. Do not push the orodispersible tablet through the foil as it is fragile and easily broken.
  2. Remove the orodispersible tablet with dry hands by peeling the backing off the foil and tipping the tablet onto your dry hands.
  3. Place the orodispersible tablet directly on your tongue as soon as it is taken out of the foil. The orodispersible tablet will immediately start to melt on the tongue. It can then be swallowed with or without water.
Do not cut, break or crush the orodispersible tablet.

You may stop taking Loperamide once you feel better or if you have no more diarrhoea unless instructed otherwise by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • acute dysentery (inflammation and infection of the intestines that causes severe diarrhoea, blood or mucus in stools, and high fever)
  • acute ulcerative colitis (inflammation of the large intestines)
  • colitis (inflammation of the lining of the colon [large intestine]) caused by certain bacteria or after taking antibiotics
  • bowel disorders e.g. constipation, swollen stomach, stomach pain without diarrhoea, ileus (a condition where the bowel does not work properly)
as Loperamide may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • liver disease
  • acquired immune deficiency syndrome (AIDS)
  • history of drug abuse
  • heart rhythm problems
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to a child. Children may be more sensitive to the side effects.

Your body loses large amounts of fluids and salts when you have diarrhoea. Ensure to replace the fluids and salts lost by drinking plenty of water and oral rehydration solution.

If your symptoms do not improve within 2 days of taking Loperamide, stop taking this medicine and consult your doctor.
What side effects could I experience?
Loperamide may cause dizziness, drowsiness, or tiredness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, nausea, stomach discomfort, constipation, indigestion, vomiting, and dry mouth.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • signs and symptoms of serious gastrointestinal problems e.g. constipation with severe stomach pain, swollen stomach, passing bloody stools
  • signs and symptoms of pancreatitis (inflammation of the pancreas) e.g. upper abdominal pain, tenderness when touching the abdomen, abdominal pain that may radiate to your back, fever, rapid pulse, nausea, vomiting
  • irregular or abnormal heartbeat, chest pain, loss of consciousness
  • rashes, breathlessness, swelling of the face, eyes or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for fungal infection e.g. itraconazole, ketoconazole
  • medicines for irregular heartbeat e.g. amiodarone, procainamide, quinidine
  • medicines for mood disorders e.g. haloperidol, thioridazine
  • moxifloxacin (certain antibiotic)
  • gemfibrozil (cholesterol-lowering medicine)
  • ritonavir (medicine for HIV infection)
  • desmopressin (medicine used to control night-time bedwetting)
This list does not include all medicines that may interact with Loperamide.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on loperamide - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in