Diopolol Adverse Reactions

Potential Adverse Reactions: A variety of adverse reactions not listed (see Side Effects) have been reported with other beta-adrenergic blocking agents and should be considered potential adverse reactions to bisoprolol extended release tablets.
Central Nervous System: Reversible mental depression progressing to catatonia; an acute reversible syndrome characterized by disorientation for time and place, short term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics.
Cardiovascular: Intensification of AV block.
Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.
Heart Failure: In the MERIT-HF study, serious adverse events and adverse events leading to discontinuation of study medication were systematically collected. Following are the adverse events in the MERIT-HF study that occurred at an incidence of equal to or greater than 1% in the bisoprolol extended release tablets group and greater than placebo by more than 0.5%, regardless of the assessment of causality: Dizziness/vertigo, bradycardia, accident and/or injury.
Other adverse events with an incidence of >1% on bisoprolol extended release tablets and as common on placebo (within 0.5%) included myocardial infarction, pneumonia, cerebrovascular disorder, chest pain, dyspnea/dyspnea aggravated, syncope, coronary artery disorder, ventricular tachycardia/arrhythmia aggravated, hypotension, diabetes mellitus/diabetes mellitus aggravated, abdominal pain, and fatigue.
It is advised to inform to doctor of any adverse reaction suffered from using this drug.