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Methylcobalamin, show a wide therapeutic range During recommended usage symptoms of overdose are not known.
High doses of alpha lipoic acid could also potentially lower blood sugar. This is often beneficial to patients who have diabetes, but it requires close monitoring of blood sugar levels.
In case of Folic acid no special procedures or antidote are likely to be needed.
Vitamin B1: Thiamine has a broad therapeutic range. Very high doses (over 10 g) have a ganglion-blocking effect, similar to that of curare, and suppress the conduction of nerve impulses.
Vitamin B6: The toxic potential of vitamin B6 can be considered as very low.
Long-term treatment (>6-12 months) of a daily dosage >50 mg vitamin B6 may, however, cause peripheral sensory neuropathy.
