Amlong Dosage/Direction for Use

Adults: Hypertension and Angina: Recommended Initial Dose: 5 mg orally once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response. The dose does not need adjusting when amlodipine is given concurrently with thiazide diuretics, β-adrenoreceptor-blocking agents or angiotensin-converting enzyme inhibitors. Amlodipine can be administered with or without food.
Elderly: Although elderly patients may have higher plasma concentration of amlodipine than younger patients, the terminal elimination half-lives are similar. Amlodipine is similarly well tolerated in elderly or younger patients. Therefore, normal dosage is recommended.
Renal Impairment: Changes in amlodipine plasma concentration are not correlated with the degree of renal impairment, therefore, the normal dosage is recommended. Amlodipine is not dialysable.
Patients with Impaired Hepatic Function: The half-life of amlodipine in patients with impaired liver function and dosage recommendation has not been established. Amlodipine should therefore be administered with caution in these patients.