Known hypersensitivity to allopurinol or to any of the ingredients of Allopac.
Patients who have developed a severe reaction to Allopac should not be restarted on the drug.
Patients with mild uratemia without symptom (uric acid <90 mg/L).
Use in lactation: There are reports which indicates that allopurinol and oxipurinol are excreted in human breastmilk. Therefore, Allopac should not be used during lactation.
Use in children: Allopac is contraindicated in children (except in malignant conditions especially leukemia and certain enzyme disorders eg, Lesch-Nyhan syndrome).