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ZYKADIA is supplied as printed hard-gelatin capsules containing 150 mg of ceritinib.
Ceritinib is a kinase inhibitor for oral administration. The molecular formula for ceritinib is C28H36N5O3ClS. The molecular weight is 558.14 g/mol.
Ceritinib is described chemically as 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine.
Ceritinib is a white to almost white or light yellow powder.
Excipients/Inactive Ingredients: colloidal silicon dioxide, low substituted hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, and hard gelatin capsule shells.
The capsule shell is composed of FD&C Blue # 2, gelatin, and titanium dioxide.
