Zodenox Drug Interactions

Not recommended: Concomitant intake with alcohol. The sedative effect may be enhanced when the product is used in combination with alcohol. This affects the ability to drive or use machines.
Take into account: Combination with CNS depressants. Enhancement of the central depressive effect may occur in cases of concomitant use with antipsychotics (neuroleptics), hypnotics, anxiolytics/sedatives, antidepressant agents, narcotic analgesics, antiepileptic drugs, anaesthetics and sedative antihistamines. Zolpidem tartrate appears to interact with sertraline. This interaction may cause increased drowsiness. Also, isolated cases of visual hallucinations were reported. In the case of narcotic analgesics enhancement of euphoria may also occur leading to an increase in psychological dependence.
CYP450 Inhibitors: Compounds which inhibit/induce certain hepatic enzymes (particularly cytochrome P450) may enhance/reduce the activity of benzodiazepines and benzodiazepine-like agents.
Other drugs: When zolpidem tartrate was administered with ranitidine or cimetidine, no significant pharmacokinetic interactions were observed.