No clinically relevant effects were observed for desloratadine doses up to 45 mg. The adverse event profile associated with overdosage is similar to that seen with therapeutic doses, but the magnitude of the effects can be higher.
In the event of overdose, consider standard measures to remove unabsorbed active substance. Symptomatic and supportive treatment is recommended. Desloratadine is not eliminated by haemodialysis; it is not known if it is eliminated by peritoneal dialysis.