Based on existing data, no clinically relevant interactions were observed when desloratadine co-administered with ketoconazole, erythromycin, azithromycin, fluoxetine and cimetidine.
There was no effect of food or grapefruit juice on the disposition of desloratadine. Xynoz tablet taken concomitantly with alcohol did not potentiate the performance impairing effects of alcohol. However, caution is recommended if alcohol is taken concomitantly.