Viacoram Dosage/Direction for Use

Posology: Oral use.
Viacoram 3.5 mg/2.5 mg is intended for initial therapy in patients with mild to moderate essential hypertension.
The recommended starting dose of Viacoram is 3.5 mg/2.5 mg once daily.
After at least four weeks of treatment, the dose may be increased to 7 mg/5 mg once daily in patients whose blood pressure is not adequately controlled with Viacoram 3.5 mg/2.5 mg.
Special populations: Patients with renal impairment (see Contraindications, Precautions and Pharmacology: Pharmacokinetics under Actions): Viacoram is contraindicated in patients with severe renal impairment (Creatinine clearance below 30 ml/min) (see Contraindications).
In patients with moderate renal impairment (Creatinine clearance between 30 ml/min to 60 ml/min), the initial recommended dose of Viacoram is 3.5 mg/2.5 mg every other day. In patients whose blood pressure is not adequately controlled, the dose of Viacoram 3.5 mg/2.5 mg may be taken once daily. If necessary, the dose may be increased in patients insufficiently controlled. The usual medical follow-up includes monitoring of creatinine and potassium (see Precautions and Pharmacology: Pharmacokinetics under Actions).
Patients with hepatic impairment (see Precautions and Pharmacology: Pharmacokinetics under Actions): Caution should be exercised when prescribing Viacoram to patients with severe hepatic impairment.
Older people (see Precautions and Pharmacology: Pharmacokinetics under Actions): The efficacy and safety of Viacoram have been established in older people. Caution should be exercised at initiation depending on renal function.
After initiation of the treatment, renal function should be monitored before increase of the dosage, particularly in patients aged 75 years and above. The usual medical follow-up should include monitoring of creatinine and potassium.
Paediatric population: The safety and efficacy of Viacoram in children aged below 18 years have not been established. No data are available.
Method of administration: The tablet of Viacoram should be taken as a single dose, preferably in the morning and before a meal.