Patients with a history of severe or life-threatening hypersensitivity to the active substance or to any of the excipients listed in Description (see Precautions).
Patients with interstitial pneumonitis or pulmonary fibrosis (see Precautions).
The combination of Vectibix with oxaliplatin-containing chemotherapy is contraindicated for patients with mutant RAS mCRC or for whom RAS mCRC status is unknown (see Precautions).