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Atenolol crosses the placental barrier and appears in cord blood. No studies have been performed on the use of atenolol in the 1st trimester and the possibility of foetal injury cannot be excluded.
Atenolol has been used under close supervision for the treatment of hypertension in the 3rd trimester. Administration of atenolol for longer period to pregnant women in the management of mild to moderate hypertension has been associated with intrauterine growth retardation. The use of atenolol in women who are, or may are, or may become pregnant, requires that the anticipated benefit be weighed against the possible risks, particularly in the 1st and 2nd trimesters.
There is significant accumulation of atenolol in breast milk. Caution should be exercised when atenolol is administered to a nursing mother.
