Uptravi Description

Each round film-coated tablet contains 200 micrograms or multiples thereof (respectively 400, 600, 800, 1000, 1200, 1400, or 1600 micrograms) selexipag. The film-coated tablets are not light sensitive.
Selexipag is a pale yellow crystalline powder that is practically insoluble in water. In the solid state selexipag is very stable, is not hygroscopic, and is not light sensitive.
UPTRAVI (selexipag) is a selective non-prostanoid prostacyclin IP receptor agonist. The chemical name of selexipag is 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl) acetamide.
The molecular formula: C₂₆H₃₂N₄O₄S.
The molecular weight: 496.62 mg/mol.
Excipients/Inactive Ingredients: The tablets include the following inactive ingredients: mannitol, maize starch, hydroxypropylcellulose, and magnesium stearate.
The tablets are film coated with a coating material containing hypromellose, propylene glycol, titanium dioxide, and carnauba wax. In addition, tablets may contain iron oxide red, iron oxide yellow, or iron oxide black.