Unihist Syrup may cause drowsiness and may increase the effects of alcohol. Drowsiness may continue the following day. Those affected should not drive or operate machinery; alcohol should be avoided. Use with caution in patients with renal or hepatic impairment and in patients with epilepsy. Phenylephrine has an excessive vasopressor response that may cause a prolonged rise in blood pressure. It induces tachycardia or reflect bradycardia and should therefore be avoided in severe hyperthyroidism and used with caution in severe ischaemic heart disease. Patients with diabetes mellitus or prostatic hyperplasia should also avoid Phenylephrine.
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