ULTRACET is contraindicated: in all children younger than 12 years of age; children younger than 18 years to treat pain after surgery to remove the tonsils and/or adenoids; in patients who have previously demonstrated hypersensitivity to tramadol, paracetamol, any other component of this product or opioids; in cases of acute intoxication with alcohol, hypnotics, narcotics, centrally acting analgesics, opioids or psychotropic drugs; in patients using monoamine oxidase inhibitors (MAOIs) concurrently or within the last 14 days; adolescents between 12 and 18 years who are obese or have conditions such as obstructive sleep apnea or severe lung disease, which may increase the risk of serious breathing problems; in patients with significant respiratory depression (see Precautions).