Tri-Luma Description

Each gram of TRI-LUMA Cream contains Active: fluocinolone acetonide 0.01 % (0.1 mg), hydroquinone 4% (40 mg), and tretinoin 0.05% (0.5 mg).
TRI-LUMA Cream (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) contains fluocinolone acetonide, USP, hydroquinone, USP, and tretinoin, USP, in a hydrophilic cream base for topical application.
Fluocinolone acetonide is a synthetic fluorinated corticosteroid for topical dermatological use and is classified therapeutically as an anti-inflammatory. It is a white crystalline powder that is odourless and stable in light.
The chemical name for fluocinolone acetonide is: (6α-,11β,16α)-6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,-4-diene-3,20-dione.
The molecular formula is C₂₄H₃₀F₂O₆ and molecular weight is 452.50.
Hydroquinone is classified therapeutically as a depigmenting agent. It is prepared from the reduction of p-benzoquinone with sodium bisulfite. It occurs as fine white needles that darken on exposure to air.
The chemical name for hydroquinone is: 1,4-benzenediol.
The molecular formula is C₆H₆O₂ and molecular weight is 110.11.
Tretinoin is all-trans-retinoic acid formed from the oxidation of the aldehyde group of retinene to a carboxyl group. It occurs as yellow to light-orange crystals or crystalline powder with a characteristic odor of ensilage. It is highly reactive to light and moisture and should be stored at a cool temperature. Tretinoin is classified therapeutically as a keratolytic. The chemical name for tretinoin is: (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
The molecular formula is C₂₀H₂₈O₂ and molecular weight is 300.44.
Excipients/Inactive Ingredients: butylated hydroxytoluene, cetyl alcohol, citric acid, glycerin, magnesium aluminum silicate, methyl gluceth-10, methyl-paraben , Arlacel 165, propylparaben 0.02% (0.2mg), purified water, sodium metabisulfite, stearic acid, and stearyl alcohol.