Tremfya Patient Counseling Information

Instructions for preparation and giving an injection of TREMFYA: Pre-filled syringe at-a-glance: Before injection: Plunger: Do not hold or pull plunger at any time; Safety guard; Finger flange; Body: Hold syringe body below finger flange; Viewing window; Needle cover: Do not remove until you are ready to inject TREMFYA (see Step 2).
After injection: Plunger locks; Safety guard activates; Needle retracts into the body.
You will need these supplies: 1 Alcohol swab, 1 Cotton ball or gauze pad, 1 Adhesive bandage, 1 Sharps container (see Step 3).
1. Prepare for your injection: Inspect carton: Remove carton with the pre-filled syringe from the refrigerator.
Keep the pre-filled syringe in the carton and let it sit on a flat surface at room temperature for at least 30 minutes before use.
Do not warm any other way.
Check the expiration date ('EXP') on the back panel of the carton.
Do not use if the expiration date has passed.
Do not inject if the perforations on the carton are broken.
Call your doctor or pharmacist for a refill.
Choose injection site: Select from the following areas for your injection: Front of thighs (recommended); Lower abdomen: Do not use the 2-inch (5-centimetre) area around belly-button; Back of upper arms (if a caregiver is giving you the injection).
Do not inject into skin that is tender, bruised, red, scaly or hard.
Do not inject into areas with scars or stretch marks.
Clean injection site: Wash your hands well with soap and warm water.
Wipe your chosen injection site with an alcohol swab and allow it to dry.
Do not touch, fan or blow on the injection site after you have cleaned it.
Inspect liquid: Take the pre-filled syringe out of the carton.
Check the liquid in the viewing window. It should be clear to slightly yellow and may contain tiny white or clear particles. You may also see one or more air bubbles. This is normal.
Do not inject if the liquid is cloudy or discolored, or has large particles. If you are uncertain, call your doctor or pharmacist for a refill.
2. Inject TREMFYA using the pre-filled syringe: Remove needle cover: Hold syringe by the body and pull needle cover straight off. It is normal to see a drop of liquid.
Inject within 5 minutes of removing the needle cover.
Do not put needle cover back on, as this may damage the needle.
Do not touch needle or let it touch any surface.
Do not use the TREMFYA pre-filled syringe if it is dropped. Call your doctor or pharmacist for a refill.
Position fingers and insert needle: Place your thumb, index and middle fingers directly under the finger flange.
Do not touch plunger or area above finger flange as this may cause the needle safety device to activate.
Use your other hand to pinch skin at the injection site.
Position syringe at about a 45 degree angle to the skin.
It is important to pinch enough skin to inject under the skin and not into the muscle.
Insert needle with a quick, dart-like motion.
Release pinch and reposition hand: Use your free hand to grasp the body of the syringe.
Press plunger: Place thumb from the opposite hand on the plunger and press the plunger all the way down until it stops.
Release pressure from plunger: The safety guard will cover the needle and lock into place, removing the needle from your skin.
3. After your injection: Throw the used pre-filled syringe away: Put your used syringe in a sharps disposal container right away after use.
Make sure you dispose of the bin as instructed by your doctor or nurse when the container is full.
Check injection site: There may be a small amount of blood or liquid at the injection site. Hold pressure over your skin with a cotton ball or gauze pad until any bleeding stops.
Do not rub the injection site.
If needed, cover injection site with a bandage.
Your injection is now complete.