Toujeo Caution For Usage

Incompatibilities: Toujeo must not be mixed or diluted with any other insulin or other medicinal products. Mixing or diluting Toujeo changes its time/action profile and mixing causes precipitation.
Special precautions for disposal and other handling: Before first use, the pen must be stored at room temperature at least 1 hour before use.
Before using Toujeo SoloStar pre-filled pen, the Instructions for Use under Patient Counselling Information must be read carefully. Toujeo SoloStar pre-filled pen has to be used as recommended in these Instructions for Use (see Dosage & Administration and Patient Counselling Information). Instruct patients to perform a safety test as described in Step 3 of the Instructions for Use under Patient Counselling Information. If they don't, the full dose might not be delivered. If this occurs, patients should increase the frequency of checking their blood glucose levels and might need to administer additional insulin.
The cartridge should be inspected before use. It must only be used if the solution is clear, colourless, with no solid particles visible, and if it is of water-like consistency. Since Toujeo is a clear solution, it does not require resuspension before use.
Insulin label must always be checked before each injection to avoid medication errors between Toujeo and other insulins. The strength "300" is highlighted in honey gold on the label (see Precautions).
Patients should be informed that the dose counter of Toujeo SoloStar pre-filled pen shows the number of units of Toujeo to be injected. No dose re-calculation is required.
The Toujeo SoloStar pen contains 450 units of Toujeo. It delivers doses of 1-80 units per injection, in steps of 1 unit.
If safety tests are not performed before the first use of a new pen, insulin underdose can occur.
A syringe must never be used to withdraw Toujeo from the cartridge of the SoloStar pre-filled pen or severe overdose can result (see Dosage & Administration, Precautions and Overdosage).
A new sterile needle must be attached before each injection. Needles must be discarded immediately after use. Needle must not be re-used. Re-use of needles increases the risk of blocked needles which may cause underdosing or overdosing. Using a new sterile needle for each injection also minimizes the risk of contamination and infection. In the event of blocked needle, the patients must follow the instructions described in Step 3 of the Instructions for Use under Patient Counselling Information (see Dosage & Administration, Precautions and Patient Counselling Information).
Used needles should be thrown away in a puncture resistant container or disposed of in accordance with local requirements.
Empty pens must never be reused and must be properly discarded.
To prevent possible transmission of disease, insulin pen should never be used by for more than one person, even when the needle is changed (see Dosage & Administration).