Enhanced blood glucose-lowering effect w/ antihyperglycaemics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates, sulfonamides. Reduced blood glucose-lowering effect by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, oestrogens & progestogens, phenothiazine derivatives, somatropin, sympathomimetics [eg, epinephrine (adrenaline), salbutamol, terbutaline], thyroid hormones, atypical antipsychotics (eg, clozapine, olanzapine), PIs. Potentiated or weakened blood glucose-lowering effect w/ β-blockers, clonidine, lithium salts or alcohol. Hypoglycemia sometimes followed by hyperglycemia w/ pentamidine. Reduced or absent signs of adrenergic counterregulation w/ sympatholytics eg, guanethidine, reserpine.