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Pharmacology: Pharmacodynamics: THELBAN (Albendazole) is an anthelmintic exhibits vermicidal, ovicidal and larvacidal activity.
Pharmacokinetics: Albendazole is poorly absorbed from gastro-intestinal tract after oral administration, but rapidly undergoes extensive first-pass metabolism. The principal metabolite (albendazole sulfoxide) has anthelmintic activity, and a plasma half-life of about 8 ½ hours, it is excreted in the urine together with other metabolites including albendazole sulfone and the 2-amino-sulfoxide and 2-amino sulfone.
