Animal reproduction studies have not been conducted with dihydrocodeine. It is also not known whether dihydrocodeine can cause fetal harm when administered to pregnant women or can affect reproduction capacity in males and females.
Dihydrocodeine should be given to a pregnant woman only if clearly needed.
Because of the potential for serious adverse reactions in nursing infants from dihydrocodeine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.