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Monotherapy: Sulbactam/cefoperazone is indicated for the treatment of the following infections when caused by susceptible organisms: Respiratory Tract Infections (Upper and Lower), Urinary Tract Infections (Upper and Lower), Peritonitis, Cholecystitis, Cholangitis, and Other Intra-abdominal infections, Septicemia, Meningitis, Skin and Soft Tissue Infections, Bone and Joint Infections, Pelvic Inflammatory Disease, Endometritis, Gonorrhea, and Other Infections of the Genital Tract.
Combination Therapy: Because of the broad spectrum of activity of sulbactam/cefoperazone, most infections can be treated adequately with this antibiotic alone. However, sulbactam/cefoperazone may be used concomitantly with other antibiotics if such combinations are indicated. If an aminoglycoside is used (see Incompatibilities - Aminoglycosides under Cautions for Usage), renal function should be monitored during the course of therapy (see Use in Renal Dysfunction under Dosage & Administration).
