Starflu Special Precautions

Convulsion and delirium like neuropsychiatric events have been reported during oseltamivir administration in patients with influenza, predominately in children and adolescent. In rare cases these events resulted in accidental injury. The contribution of oseltamivir to these events are unknown and these have also been reported in patients with influenza who were not taking oseltamivir. Patients especially children and adolescent, should be closely monitored for signs of abnormal behavior.
There is no evidence for efficacy of oseltamivir in any illness caused by agents other than influenza viruses Types A and B.
Dose adjustment is recommended for patients with creatinine clearance of 10-30mL/min for the treatment of influenza and prophylaxis of influenza. No dosing recommendation is available for patients undergoing routine haemodialysis and continuous peritoneal dialysis with end stage renal disease and for patients with creatinine clearance ≤ 10mL/min.