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Each single-use vial contains 350 mg of amivantamab per 7 mL vial (or 50 mg of amivantamab per mL).
RYBREVANT is available as a colorless to pale yellow preservative-free liquid concentrate for intravenous infusion after dilution.
Amivantamab is a fully-human immunoglobulin G1(IgG1)-based bispecific antibody directed against the epidermal growth factor (EGF) and mesenchymal-epidermal transition (MET) receptors, produced by a mammalian cell line (Chinese Hamster Ovary [CHO]) using recombinant DNA technology (see Pharmacology: Pharmacodynamics: Mechanism of action under Actions).
Excipients/Inactive Ingredients: EDTA disodium salt dihydrate, L-Histidine, L-Histidine hydrochloride monohydrate, L-Methionine, Polysorbate 80, Sucrose, Water for Injection.
