RejuvaSil

RejuvaSil Mechanism of Action

Manufacturer:

Celestemal Pharma

Distributor:

Antah Pharma
Full Prescribing Info
Action
RejuvaSil is a topical liquid silicone gel with Emu Oil (an anti-inflammatory), Squalane (a moisturizer), and Vitamin C (for scar discoloration) that is used to improve the appearance of surgical and traumatic scars (including normal post op scars, hypertrophic scars and keloid scars) and burns. It is applied to clean dry scar up to 3 times daily. The mechanism of action includes hydration and occlusion. RejuvaSil dries to a thin semi-occlusive film on the skin.
Cyclomethicone and Dimethicone Cross Polymer (silicones in liquid form) create a hydrated occluded environment decreases capillary activity by reducing fibroblast induced collagen deposition and scar hypertrophy decreasing hyperemia minimizes fibroblast production of collagen and promotes wound flattening.
Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester which has anti-oxidant activity, inhibiting lipid peroxidation. Studies have shown Vitamin C to be a clarifying and brightening agent to the skin by inhibiting melanogenesis (the production of pigment) thereby promoting a more even skin tone. Unlike ascorbic acid, it will not exfoliate or irritate skin. For scars it basically has been shown to reduce redness.
Emu Oil is approximately 70% unsaturated fatty acids. The largest component is oleic acid - a mono-unsaturated fatty acid. Emu oil also contains about 20% linolenic (Omega 6) acid and 1-2% linolenic (Omega 3) acid. There is some evidence to suggest that the oil may have medicinal benefit. Emu oil has been shown in studies to aid in reducing scar formation in healed burn wounds, due to its strong anti-inflammatory properties. Emu oil is a complete neutral lipid, since emu oil lacks phospholipid, making it highly penetrating to the skin.
Squalane is used as a natural moisturizer and anti-oxidant. It penetrates the skin quickly, does not leave a greasy feeling on the skin and blends well with other oils and vitamins. Squalane aids in softening the scar tissue resulting in a softer scar.
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