Fertility: No human data on the effect of ravidasvir on fertility are available. No effect on fertility was seen in rats (see Pharmacology: Toxicology: Preclinical Safety Data under Actions).
Pregnancy: Teratogenic and/or embryotoxic effects have been demonstrated in rabbits exposed to ravidasvir. There are very limited data on exposure to Ravida during pregnancy in humans. Use of Ravida is not recommended during pregnancy.
Women of childbearing potential should use effective contraception methods before starting treatment with Ravida and continue until 1 month after completion of treatment (see Pharmacology: Toxicology: Preclinical Safety Data under Actions).
Breast-feeding: Ravidasvir has been shown to pass through the blood-milk barrier in rats (see Pharmacology: Toxicology: Preclinical Safety Data under Actions). There are no data in humans. Use of Ravida is not recommended during breast-feeding.